Purification engineering technology research center of Sichuan Province Natural Medicine
四川省天然藥物分離純化工程技術(shù)研究中心
文獻(xiàn)
Qi Cui.et al.Synergistic coupling of ultrasonic cavitation with tailored deep eutectic solvent systems for intensified extraction of Scutellaria Radix flavonoids: Modelling and optimization by genetic algorithm[J].Ultrasonics Sonochemistry,2025(119):107386
本文來(lái)自： 發(fā)布時(shí)間：2025-09-04
發(fā)表期刊：Ultrasonics Sonochemistry
發(fā)表時(shí)間：2025
Abstract:
Deep eutectic solvents (DESs) are increasingly recognized as viable environmentally friendly alternatives to traditional organic solvents because of their low toxicity and exceptional dissolving capabilities. In this research, 12 DESs were synthesized and systematically integrated with ultrasonic-assisted extraction (UAE) to extract flavonoids from Scutellaria Radix. Comprehensive screening revealed that the optimal DES outperformed conventional solvents (water and 70 % ethanol) in extraction efficiency. Through statistical optimization, including single-factor experiments, response surface methodology, and an artificial neural network–genetic algorithm, we achieved remarkable extraction yields for six target flavonoids: scutellarin (3.88 ± 0.37), baicalin (137.67 ±8.61), wogonoside (13.40 ± 0.58), baicalein (27.95 ± 1.12), wogonin (15.95 ± 1.48), and chrysin (1.81 ± 0.21 mg/g). These values represented significant improvements over conventional extraction methods. Subsequent enrichment processes yielded flavonoid recovery rates of 76.80–85.13 %, and demonstrated excellent DES recyclability over four consecutive extraction cycles. In sum, this work establishes a sustainable, high-efficiency platform for phytochemical extraction, offering substantial advances in sustainable natural product processing through intelligent solvent design and process optimization.
https://doi.org/10.1016/j.ultsonch.2025.107386
聯(lián)系我們
4000-369-963 028-85370565
3004654993@qq.com
四川省 成都市 武侯區(qū) 武科西二路8號(hào)
關(guān)于普思
產(chǎn)品
技術(shù)服務(wù)
普思生物為您提供中藥化學(xué)對(duì)照品、高純化學(xué)試劑、天然產(chǎn)物化合物庫(kù)等優(yōu)質(zhì)產(chǎn)品，
僅用于科學(xué)研究、工業(yè)應(yīng)用等非醫(yī)療用途范疇，不可用于人的臨床治療或試驗(yàn)，非藥用，非食用。
友情鏈接：全球化學(xué)品供應(yīng)商搜索 蓋德化工網(wǎng) 成都普思生物科技股份有限公司版權(quán)所有 蜀ICP備08100078號(hào)
咨詢
熱線
4000-369-963
7*24小時(shí)客服服務(wù)熱線
關(guān)注
微信
關(guān)注官方微信